Julien is currently a research scientist at INRAE Micalis institute settled in Paris-Saclay campus, where he works on projects related to the interactions between food and human microbiomes in a nutrition and health perspective.
After several internships in microbiology at Institut Pasteur (Patrick Grimont, Philippe Glaser, Sylvain Brisse), Julien Tap went to Joel Doré’s Lab to do a PhD headed by Marion Leclerc (Jan 2007 to Dec 2009). His main project was to study dietary fiber impact on human gut microbiota using notably metagenomic and metatranscriptomic approaches.
Since his PhD, his research interest focused on interactions between nutrition, gut microbiota, and human health. This allowed him to work with different AP-HP clinicians like Pr Karine Clément and Pr Iradj Sobhani. As post-doc did at EMBL in Peer Bork’s group and at INRAE Metagenopolis unit (Joel Doré, Dusko Ehrlich), as well as Danone Research, he used several approaches like numerical ecology and machine learning technics to untangle big omics data with clinical and dietary data.
Selected publications
- Tap et al. Global branches and local states of the human gut microbiome define associations with environmental and intrinsic factors. 2023. Nature communications
- Tap et al. The Human Gut Microbiota in all its States: From Disturbance to Resilience. Comprehensive Gut Microbiota, Elsevier, pp.161-178, 2022.
- Tap et al. Diet and gut microbiome interactions of relevance for symptoms in irritable bowel syndrome. 2021. Microbiome
- Tap et al. Identification of an intestinal microbiota signature associated with severity of irritable bowel syndrome. 2017. Gastroenterology
- Tap et al. Gut microbiota richness promotes its stability upon increased dietary fibre intake in healthy adults . 2015. Environmental microbiology
