My name is Raphaël Charron and I am currently in the third and last year of my PhD in the B3D Team at the Micalis Institute. I am working between two labs, the second one being the AB2R Team at the ANSES laboratory of Fougères.
My project aims to understand how biofilms, both at individual and collective scales, influence adaptation to biocides and their impact on the emergence of antibiotic cross-resistant bacteria.
Biofilms are the predominant form of bacterial life on Earth and dominate specific environments such as food-processing industries. They have a particular effect on bacterial metabolism, impacting their adaptation to stresses and potential resistance to certain antimicrobial molecules, such as biocides. However, biocides are widely used in food processing industries, and some studies suggest that bacterial adaptation to these molecules can sometimes have collateral effects on their antibiotic resistance. Nevertheless, the majority of these studies are conducted on planktonic bacteria, which are not representative of the primary form of life when encountering biocides.
Thus, my project is integrated into the One Health approach, aiming to limit the emergence of antimicrobial resistance (AMR), by understanding how bacteria adapt when embedded in biofilms, in comparison to their planktonic lifestyle.
raphael-charron
